Ferric oxyhydroxide
Ferric Oxyhydroxide, Ferrlecit, Infed, Velphoro, Venofer (ferric oxyhydroxide) is a small molecule pharmaceutical. Ferric oxyhydroxide was first approved as Infed on 1982-01-01.
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Commercial
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FDA
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Velphoro
Indications
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Clinical
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33 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anemia | D000740 | EFO_0004272 | D64.9 | — | 3 | 5 | 9 | 2 | 18 |
| Iron-deficiency anemia | D018798 | — | D50 | 1 | 1 | 3 | 8 | 1 | 13 |
| Iron deficiencies | D000090463 | — | E61.1 | 1 | 1 | 3 | 8 | 1 | 13 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | 1 | 1 | — | 4 | 1 | 7 |
| Renal insufficiency | D051437 | — | N19 | 1 | — | — | 4 | 1 | 6 |
| Hyperphosphatemia | D054559 | — | — | — | 1 | 3 | 1 | 2 | 6 |
| Chronic renal insufficiency | D051436 | — | N18 | — | — | 1 | 3 | — | 4 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | — | 1 | 2 | — | 3 |
| Deficiency diseases | D003677 | EFO_1001067 | E63 | — | 1 | 1 | 1 | — | 2 |
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | — | 2 | — | 2 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | — | — | 1 | — | — | 1 |
| Neoplasms | D009369 | — | C80 | — | — | 1 | — | — | 1 |
| Multiple myeloma | D009101 | — | C90.0 | — | — | 1 | — | — | 1 |
| Lymphoma | D008223 | — | C85.9 | — | — | 1 | — | — | 1 |
| Precancerous conditions | D011230 | — | — | — | — | 1 | — | — | 1 |
| Lymphoproliferative disorders | D008232 | Orphanet_2442 | D47.9 | — | — | 1 | — | — | 1 |
| Plasma cell neoplasms | D054219 | — | — | — | — | 1 | — | — | 1 |
| Plasmacytoma | D010954 | — | C90.3 | — | — | 1 | — | — | 1 |
| Inflammatory bowel diseases | D015212 | EFO_0003767 | — | — | — | 1 | — | — | 1 |
| Intestinal diseases | D007410 | — | K63.9 | — | — | 1 | — | — | 1 |
Indications Phases 1
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ferric oxyhydroxide |
| INN | _ |
| Description | Sucroferric oxyhydroxide, sold under the brand name Velphoro, is a non-calcium, iron-based phosphate binder used for the control of serum phosphorus levels in adults with chronic kidney disease (CKD) on haemodialysis (HD) or peritoneal dialysis (PD). It is used in form of chewable tablets.
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| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 12134-57-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3039566 |
| ChEBI ID | — |
| PubChem CID | 91502 |
| DrugBank | — |
| UNII ID | 87PZU03K0K (ChemIDplus, GSRS) |
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Safety
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3,742 adverse events reported
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