Ferric oxyhydroxide
Ferric Oxyhydroxide, Ferrlecit, Infed, Velphoro, Venofer (ferric oxyhydroxide) is a small molecule pharmaceutical. Ferric oxyhydroxide was first approved as Infed on 1982-01-01.
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Commercial
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Trade Name
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Ferric complex in sucrose, Ferrlecit, Infed, Velphoro, Venofer (discontinued: Dexferrum, Iron dextran, Proferdex, Venofer)
Drug Products
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EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| ferrlecit | New Drug Application | 2025-06-06 |
| infed | New Drug Application | 2024-10-14 |
| iron dextran | New Drug Application | 2025-01-08 |
| velphoro | New Drug Application | 2024-12-12 |
| venofer | New Drug Application | 2022-07-25 |
| venofer (iron sucrose) | New Drug Application | 2024-04-19 |
Indications
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Agency Specific
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Clinical
Clinical Trials
283 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anemia | D000740 | EFO_0004272 | D64.9 | — | — | 2 | 1 | — | 3 |
| Pregnancy complications | D011248 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Iron-deficiency anemia | D018798 | — | D50 | — | — | 2 | — | — | 2 |
| Deficiency diseases | D003677 | EFO_1001067 | E63 | — | — | 2 | — | — | 2 |
| Iron deficiencies | D000090463 | — | E61.1 | — | — | 2 | — | — | 2 |
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | — | 1 | — | — | 1 |
| Crohn disease | D003424 | EFO_0000384 | K50 | — | — | 1 | — | — | 1 |
| Inflammatory bowel diseases | D015212 | EFO_0003767 | — | — | — | 1 | — | — | 1 |
| Colitis | D003092 | EFO_0003872 | K52.9 | — | — | 1 | — | — | 1 |
| Intestinal diseases | D007410 | — | K63.9 | — | — | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ferric oxyhydroxide |
| INN | _ |
| Description | Sucroferric oxyhydroxide, sold under the brand name Velphoro, is a non-calcium, iron-based phosphate binder used for the control of serum phosphorus levels in adults with chronic kidney disease (CKD) on haemodialysis (HD) or peritoneal dialysis (PD). It is used in form of chewable tablets.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 12134-57-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3039566 |
| ChEBI ID | — |
| PubChem CID | 91502 |
| DrugBank | — |
| UNII ID | 87PZU03K0K (ChemIDplus, GSRS) |
Target
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Trends
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Safety
Black-box Warning
Black-box warning for: Iron dextran
Adverse Events
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2,375 adverse events reported
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